Drug Eluting Stents

Olexander R&D Inc. has developed proprietary coating methods and technology to uniformly and reproducibly coat neuro, coronary and peripheral stents. Coating services are provided for both device manufacturers and academic institutions for a variety of applications. We are experts on a wide range of coating technologies from the popular Sono-Tek ultrasonic atomizers to less known but effective tooling used for difficult chemistries with high viscosities. We also utilize a host of special handling devices that allow us to coat stents without flipping! Response to customer needs and requirements is paramount and we will provide services ranging from coating formulation (drug, no drug, polymer, solvent carrier) to stent crimping and sterilization. We have coating experience in processing both permanent (biostable) and biodegradable polymeric formulations on metallic and biodegradable stent substrates. We have coated a variety of stent sizes including small configurations for mouse and neuro implantation to large diameter peripheral devices with a 7.00 mm diameter and an overall length of 100 mm.

Olexander R&D Inc. has hands on experience in coating a variety of drug compositions and drug combinations including Sirolimus (Rapamycin), Everolimus, Biolimus A9, Zotarolimus, Paclitaxel, Pimecrolimus, Trapidil, and proprietary protein drugs.

Olexander R&D Inc. will support customers in all phases of their development. We have supported drug device development companies seeking to coat a variety of devices with their specific drugs. We provide coated components and coating technology to customers, thereby saving the customer both process development time and eliminating the need to purchase custom specific and expensive tooling and process equipment.

Olexander Inc will provide the following key services:

  • Coat stents with polymer or polymer and drug
  • Provide coating weights of polymer
  • Provide formulation guidance, including the selection of polymer, solvent, and drug to polymer ratio
  • Elution Analysis

In addition, Olexander R&D Inc., has the capabilities to provide the following secondary services:

  • Inspection and sorting both bare metal stents (BMS) and biodegradable stents
  • Cleaning stents
  • The application of primer(s)
  • Providing stents
  • Providing balloon catheters
  • Crimping of stents onto catheters
  • Packaging
  • Sterilization
  • Other unique customer services

Here are some of our publicized projects:

“Mouse Stent Project.”