Stent Coating Services

Olexander R&D Inc. has developed proprietary coating methods and technology to uniformly and reproducibly coat neuro, coronary and peripheral stents.  Olexander R&D Inc. provides coating services for both device manufacturers and academic institutions for a variety of applications.  Response to customer needs and requirements is paramount and we will provide services ranging from coating formulation (drug, no drug, polymer, solvent carrier) to stent crimping and sterilization.  Olexander R&D Inc. has coating experience in coating both (1) permanent, biostable, and (2) biodegradable polymeric formulations on metallic and biodegradable stent substrates.  Olexander R&D Inc. has coated a variety of stent sizes including small configurations for mouse implantation and drug testing, a “mouse stent” with a 0.635 mm diameter and an overall length of 2.5 mm; and large diameter peripheral devices with a 7.00 mm diameter and an overall length of 100 mm.

Olexander R&D Inc. has experience in coating a variety of drug compositions and drug combinations including Sirolimus (Rapamycin), Everolimus, Biolimus A9, Zotarolimus, Paclitaxel, Pimecrolimus, Trapidil, and proprietary protein drugs.

Olexander R&D Inc. will support customers in all phases of their development and has supported drug device development companies seeking to coat a variety of devices with their specific drugs.  Olexander R&D Inc. provides coating technology to customers, thereby saving the customer both process development time and eliminating the need to purchase custom specific and expensive tooling and process equipment.

Olexander R&D Inc. will provide the following key services:

  • Coat stents with polymer or polymer and drug
  • Provide coating weights of polymer, drug, by use of 0.1 microgram Mettler UMX5 balance
  • Provide formulation guidance, including the selection of polymer, solvent, and drug to polymer ratio
  • In addition, Olexander R&D Inc., has the capabilities to provide the following secondary services
  • Inspection and sorting both bare metal stents (BMS) and biodegradable stents
  • Cleaning stents
  • The application of primer
  • Providing balloon catheters
  • Crimping of stents onto catheters
  • Packaging, double pouch (outside pouch – Aluminum foil), with appropriate desiccant
  • Sterilization
  • Other unique customer services

 

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